Habitus: Superficially similar to species of the Adhemarius dariensis species-group but Amplypterus panopus panopus is distinctive in the broad, sharply delineated, parallel-sided, ash-pink band across the forewing and similarly coloured broad markings on the anterior half of the abdomen. These bands contrast with the dark chocolate-brown colour of the thorax, forewing bases and distal half of the abdomen. At rest, these bands divide the moth into three stripes, two dark bands separated by a pale band. Apex broadly of hindwing rounded (pointed in Amplypterus mansoni). Unlike Adhemarius dariensis and its relatives, the forewing upperside of Amplypterus panopus panopus lacks the subbasal spot and the tornal patch is developed into a poorly defined eyespot; tornal eyespot better developed than in Amplypterus mansoni and the submarginal area above it with a stronger, more contrasted pattern. Outer third of hindwing upperside has a diagnostic pattern of black veins crossing an olive-green submarginal and blue-grey marginal band.
Male genitalia: Uncus with a spatulate median process. Gnathos produced into a median plate, slightly longer than broad. Valve very large, apex rounded; stridulatory scales present. Harpe a small basal ridge standing nearly at right-angles to ventral edge of valve. Phallus with a small tooth; apex with two lingulate flaps bearing setose triangular projections.
Female genitalia: Sterigma membranous except for the strongly rounded distal edge.